Accutase® solution is a novel trypsin replacement that exhibits both protease and collagenolytic activities. Accutase®maintains most cell surface antigens. It contains proteolytic and collagenolytic enzymes for cell detachment. Accutase™; Cell Detachment Solution is effective in detaching primary fibroblasts, endothelial cells, neurons, tumor cell lines, and insect cells. Performs exceptionally well in detaching cells for analysis of cell surface markers, virus growth assay, and flow cytometry as well as bioreactor scale-up.