Quickly concentrate proteins and biological samples with Thermo Scientific Pierce Protein Concentrators PES (polyethersulfone), which are disposable ultrafiltration centrifugation devices that enable fast sample recovery and a short processing time. These concentrator columns can be used with standard microcentrifuge equipment, and samples can be collected without the need for invert spinning. Samples can be concentrated with or without desalting.

Features of 10K MWCO Protein Concentrators PES include:
• Rapid protein concentration—sample concentration of 10- to 30-fold can be achieved in 10 or fewer minutes using the 0.5 mL concentrator
• Excellent protein recovery—typical protein recovery is >90% (when the sample mass is at least two-fold greater than the posted MWCO)
• Instrument-compatibility—a standard microcentrifuge with fixed-angle rotors can be used; sample can be collected and recovered without invert spinning
• Versatile—easily perform sample concentration, diafiltration, or buffer-exchange of biological samples

For easy identification, the MWCO value is etched on the side of each device. To assist with sample addition and recovery, a clear window with graduations is located on the side of each device, enabling visual determination of the retentate volume. The vertical design of the membrane allows high-flux rates, low non-specific binding, and negligible protein aggregation on the membrane, giving reliable and consistent results for processing sample volumes.

The dead-stop volume for the 0.5 mL concentrator is approximately 15 μL. To achieve >90% recovery of protein with the 0.5 mL concentrators, the minimum protein sample concentration should be 0.05 mg/mL. The 0.5 mL concentrators can be used effectively at a maximum centrifugal force of 15,000 × g, using a fixed angle centrifuge only.