Models of Human Diseases by Institute of Molecular & Cell Biology (IMCB)

Animal Research and Testing

Animal models provide an opportunity to examine human biology and diseases. We have a variety of cell lines and patient-derived xenograft models combined with appropriate animal study designs to help with your research.

Key Services

Oncology Models

• Syngenic Mouse Model
• Cell line derived Xenografts (CDX)
• Patient Derived Xenografts (PDX)
• Orthotopic Model
• Metastasis Model
• 3D Electron tomography
• Angiogenesis Models

Metabolic Diseases

• Obesity (ob/ob) and diabetes (db/db)
• Diet-induced obesity (DIO) in C57BL/6 mice

Non-alcoholic steatohepatitis (NASH) Models

• nSTZ + HFD induced NASH in mice (STAM model)
• Methionine-choline deficient (MCD) diet-induced NASH in mice
  

Respiratory Models

• Ovalbumin-Induced Allergic Airway Inflammation in mice
• Lipopolysaccharide (LPS)-Induced Pulmonary Inflammation in rats and mice
• Bleomycin-Induced Pulmonary Fibrosis
• House dust mite (HDM)-Induced Allergic Asthma in mice