Research Support Centre
Technology Platforms


Models of Human Diseases by Institute of Molecular & Cell Biology (IMCB)

Animal Research and Testing

Animal models provide an opportunity to examine human biology and diseases. We have a variety of cell lines and patient-derived xenograft models combined with appropriate animal study designs to help with your research.


Key Services

Oncology Models

  • Syngenic Mouse Model
  • Cell line derived Xenografts (CDX)
  • Patient Derived Xenografts (PDX)
  • Orthotopic Model
  • Metastasis Model
  • 3D Electron tomography
  • Angiogenesis Models

Metabolic Diseases

  • Obesity (ob/ob) and diabetes (db/db)
  • Diet-induced obesity (DIO) in C57BL/6 mice

Non-alcoholic steatohepatitis (NASH) Models

  • nSTZ + HFD induced NASH in mice (STAM model)
  • Methionine-choline deficient (MCD) diet-induced NASH in mice

Respiratory Models

  • Ovalbumin-Induced Allergic Airway Inflammation in mice
  • Lipopolysaccharide (LPS)-Induced Pulmonary Inflammation in rats and mice
  • Bleomycin-Induced Pulmonary Fibrosis
  • House dust mite (HDM)-Induced Allergic Asthma in mice