Key Capabilities |
- Fed-batch and perfusion bioreactor cultivation of mammalian cell suspension in serum-free media
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- Manufacturing grade mammalian (e.g. CHO and HEK293) cell line development and cell engineering for monoclonal antibodies and other recombinant proteins
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- Established MS-based proteomics platform for protein quantification and ID, quality control analysis and therapeutic protein characterisation
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- Devised a distinctive comprehensive glycan analytical platform based on the MALDI-TOF and HPLC systems for N-and O-glycan profiling of recombinant glycoprotein drugs
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- Multi-omics characterisation of mammalian (e.g. CHO) and microbial (e.g. E.coli, P.pastoris) cell systems
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- Developed various software platforms including programs for analysis of genomics and transcriptomic Next Generation Sequences experiments, LC-MS data pre-processing and glycan profile visualisation
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- Advanced scalable cell expansion technologies using a microcarrier platform to facilitate the goal of using stem cells for cell therapy
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