Histopathology by Advanced Molecular Pathology Lab @ IMCB

Quality Histopathology Service to Enable Your Research

Advanced Molecular Pathology Laboratory (AMPL) from Institute of Molecular & Cell Biology (IMCB) is a GLP-certified histopathology laboratory that provides an integrated array of services to biomedical and pharmaceutical industries. It brings together expertise across multiple disciplines to provide a one-stop histology services. New technologies at AMPL enable research groups to deliver innovative and cutting-edge contribution to basic as well as translational research, therapeutic target validation and drug safety evaluation.

Scope of Service

AMPL handles rodent and non-rodent tissues, we offer well-established SOPs and advanced equipment to provide histo services.

Rodent necropsy	Laser capture microdissection (LCM)*
Routine and specialised histology processing*	Tissue microarrays (TMA)*
Cryo tissue processing and cryotomy*	Veterinary pathology evaluation*
Special Staining*	Veterinary diagnostic services
Immunohistochemistry and immunofluorescence*	Quality assurance at each step of service
Antibody evaluation and optimisation	GLP in vitro toxicity testing facility (in progress)
Quality scanning and digital imaging*
Image analysis*

Key Equipment

Milestone MacroPATH D Macro Digital Imaging Olympus stereo microscope
SAKURA ® Tissue-Tek® VIP® and Tissue-Tek ® Tec™
Leica RM Microtome
Leica Autostainer
Leica IPC, IPS-Slide and cassette printer
IHC-Leica Bond-Max™ and Leica Bond-III™
Leica SCN400 scanner
Leica whole slide image analysis
Metasystem fluorescence scanner
Beecher Manual Tissue Arrayer MTA-1
Carl Zeiss PALM Microbeam
Nikon90i automated microscope bright field/fluorescent

Accreditations/ Certifications

AMPL is a GLP-certified lab certified by Singapore Accreditation Council (SAC)
Veterinary pathologists are American board certified either in pathology or toxicology