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Histopathology by Advanced Molecular Pathology Lab @ IMCB

Quality Histopathology Service to Enable Your Research

Advanced Molecular Pathology Laboratory (AMPL) from Institute of Molecular & Cell Biology (IMCB) is a GLP-certified histopathology laboratory that provides an integrated array of services to biomedical and pharmaceutical industries. It brings together expertise across multiple disciplines to provide a one-stop histology services. New technologies at AMPL enable research groups to deliver innovative and cutting-edge contribution to basic as well as translational research, therapeutic target validation and drug safety evaluation. 


Scope of Service

AMPL handles rodent and non-rodent tissues, we offer well-established SOPs and advanced equipment to provide histo services.
  • Rodent necropsy
  • Laser capture microdissection (LCM)*
  • Routine and specialised histology processing*
  • Tissue microarrays (TMA)*
  • Cryo tissue processing and cryotomy*
  • Veterinary pathology evaluation*
  • Special Staining*
  • Veterinary diagnostic services
  •  Immunohistochemistry and immunofluorescence*
  • Quality assurance at each step of service
  • Antibody evaluation and optimisation
  • GLP in vitro toxicity testing facility (in progress)
  • Quality scanning and digital imaging*
  • Image analysis*




Key Equipment

  • Milestone MacroPATH D Macro Digital Imaging Olympus stereo microscope
  • SAKURA ® Tissue-Tek® VIP® and Tissue-Tek ® Tec™
  • Leica RM Microtome
  • Leica Autostainer
  • Leica IPC, IPS-Slide and cassette printer
  • IHC-Leica Bond-Max™ and Leica Bond-III™
  • Leica SCN400 scanner
  • Leica whole slide image analysis
  • Metasystem fluorescence scanner
  • Beecher Manual Tissue Arrayer MTA-1
  • Carl Zeiss PALM Microbeam
  • Nikon90i automated microscope bright field/fluorescent



Accreditations/ Certifications

  • AMPL is a GLP-certified lab certified by Singapore Accreditation Council (SAC)
  • Veterinary pathologists are American board certified either in pathology or toxicology