Drug Discovery

High Throughput Screening by Experimental Drug Development Centre (EDDC)

High throughput screening (HTS) utilises automated equipment to enable rapid testing of large numbers of biological or chemical samples to screen for a specific target. HTS methods are used widely in the drug discovery process as a cost and time-effective means for accelerated targeted drug analysis and the screening of large compound libraries...Find out more

Structural Biology & Biophysical Screening by EDDC

Understanding protein-ligand interactions is pivotal for accelerating lead identification and structure guided lead optimisation. Our structural biology & biophysical screening platform supports target-based drug discovery projects at EDDC...Find out more

High Throughput Phenomics by EDDC

The CHiP platform at EDDC is designed to function as a shared resource that provides an integrated, state-of-the-art High-Throughput and High-Content Screening (HTS & HCS) solutions in Singapore. As pioneers in the fields of Functional and Chemical Genomics, CHiP HTS & HSC solutions have led the discovery of biologically-relevant molecular probes that have in turn paved the way for new diagnostics and therapeutics... Find out more

In-vitro Toxicology by Institute of Molecular and Cell Biology (IMCB)

As no chemical is completely risk-free, testing the harmful effects of various drugs is a quintessential component of pharmaceutical research. We offer in vivo testing (non-GLP) as well as in vitro alternatives to animal testing to cater to a wide range of research needs. With a selection of animal models and assays, we ensure accuracy in quantifying your targets’ risks, helping you take that step forward towards the development of safer ones...Find out more

RNAi High Content Imaging Screening Facility by Institute of Molecular and Cell Biology (IMCB)

Our siRNA screen platform technology aim at providing users with valuable siRNA gene leads discovery for a key biological question. We quantify cell phenotype with high content imaging or other modalities. We quantify cell phenotype with high content imaging or other modalities. We will assist users in our facility in miniaturizing, automating and designing robust cell based assay suitable from small screen of 200 siRNA in one plate or large screen of up to 20000 siRNA across 72x 384 well plates...Find out more