Background

The A*STAR Mass Spectrometry Cluster brings together a wealth of mass spec capabilities from across the Biomedical Research Council of A*STAR. Through the coordination of 30 high-end instruments across 7 existing well-established mass spec platforms, spanning 4 Research Institutes, the cluster ensures that scientists needs are met whilst ensures efficiency in spending, reduces unnecessary duplication and maximises utilisation of valuable resources. Capabilities include mass spec capabilities optimised for a comprehensive range of applications within proteomics (functional and expression), biomanufacturing (biopharma and analytics) and small molecules (including food science, pharma, bioprocess and human health).

The cluster’s team of dedicated expert staff are able consult, train, support and offer high-quality service to scientists via a range of access models (including self-use, service and collaborative projects). The cluster is supported by the Research Support Centre (RSC) for front office (e.g. marketing, enquiry handling) and back-office functions (e.g. invoicing, reporting) to ensure a professional service.

Protein Analytics

Biologics product characterisation

Alternative protein

Expression

Clinical proteomics

Quantitative proteomics (SILAC; SWATH-MS)

Functional

Target proteomics / SRM / MRM / PRM

Bio-processing

Metabolite tracing

Lipidomics

Food Science

Glyco-analytics

Impurities analysis

Human health and disease

Biomarker discovery

Skin metabolome

Pharma-ceutical

API characterisation

• Data Independent Acquisition / SWATH
• Metabolite Tracing / Metabolic Labelling
• Structural Elucidation
• Quantitative / Qualitative Analysis
• Clinical Proteomics / Metabolomics
• Customised Data Analytics

• Single / Multiple / Parallel Reaction Monitoring
• Metabolite Tracing

Bioprocess Omics Platform

Mass Spectrometry Group

Advanced Proteomics Platform

Bio-Trans

Innovations in Food and Chemical Safety

Natural Product Discovery Platform