Bioprocess Omics Platform

Technology Platforms

The Bioprocessing Technology Institute (BTI) spearheads innovative research in bioprocess science and engineering. Our interests lie in the application of advanced mass spectrometry to bio-analytical characterisation of biotherapeutic products and bioprocesses, as well as in food and nutrition applications.

Within the Bioprocess Omics Platform, we have three mass spectrometry (MS) teams of scientists specialising in:

Glycomics
Metabolomics, and
Proteomics

Our expertise and services are available to commercial organisations with similar research interests, such as biopharma, biotech, and food and consumer industrial entities. Academic entities are also welcome to explore opportunities for research collaboration with us.

Key MS Service Applications

Intact mass analysis
Peptide mapping with PTM
N-terminal sequencing
C-terminal sequencing
Identification of disulphide bonds
Site specific oligosaccharide profiling
N- and O-glycan profiling
Determination of N glycosylation site
Monosaccharide composition
Metabolite impurities profiling
Media analysis & cellular metabolites characterisation
High throughput protein composition profiling (DIA-SWATH MS)

Key Equipment

1. Ultraflex III MALDI-TOF/TOF (Bruker)

2. UPLC-TripleTOF 6600 (SCIEX)

3. NanoLC-TSQ Vantage (Thermo Scientific)

4. Orbitrap Elite (Thermo Scientific)

5. UPLC-Xevo G2-S QTOF (Waters)

6. UPLC-Xevo TQ-S (Waters)

Click here to find out more of Customised Bioprocessing Technologies

For further enquiries, please contact us enquiries@rsc.a-star.edu.sg